I just lost my 2nd motor to a similar failure. The #3 rod exited the case in a dramatic way.
Motor specs.
103 by 80 bore/stroke
Ham LE200 heads, 6800rpm limit
Dual oil coolers on a full flow system
Sequential fuel and ignition.
tuna can sump with 1/2 quart over fill level.
windage tray modified with holes at the push rod ends to aid flow back to the sump.
Large vented breather with both heads ducted
Since my first motor let loose, I have added the 2nd oil cooler and the sequential fuel and ignition Motor was balanced, with the crank turned -.010 for the new build. I also changed the rod length to a longer rod and reduced the bore by 1mm.
I am wondering if I was sucking air or it is a lack of return flow (still sucking air) that could cause the damage. The other option is RPM causing some sort of failure on a weak oil film. Looking for ideas as I don't want to go through this a 3rd time.